PROJECT TOPIC AND MATERIAL ON CHRONOMODULATED NIFEDIPINE ADMINISTRATION AND MICROVASCULAR COMPLICATIONS IN GLIMEPIRIDE-TREATED HYPERGLYCAEMIC RATS Circadian rhythm is any biological process that displays an endogenous (“built in”, self sustained) and entrainable (can be adjusted or reset) oscillation of about twenty-four hours (Halberg et al., 2003). These rhythms are driven by a circadian ...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE ACTIVITIES OF SOME ANTI FUNGAL AGENTS AGAINST DERMATOPHYTE ISOLATES FROM SCHOOL CHILDREN WI TH TI NEA CAPI TI S. The body normally hosts a variety of microorganisms including bacteria, mold-like fungi (dermatophytes) and yeast-like fungi (such as candida). Some of these are useful to the body. Others may under proper conditions multiply rapidly and cau...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE BIOAVAILABILITY STUDIES OF PARACETAMOL BRANDS IN HUMANS BIOAVAILABILITY, BIOEQUIVALENCE AND DRUG SELECTION Bioavailability and bioequivalence of drug products, and drug product selection have emerged as critical issues in pharmacy and medicine during the last three decades concern about lowering health care cost has resulted in tremendous increase...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA Increasing economic activities in many parts of the world have led to the proliferation of pharmaceutical manufacturing industries with the attendant introduction of many brands of the same drug into Market. The availability of different brands of a generic produ...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME SELECTED BRANDS OF CIPROFLOXACIN TABLETS MARKETED IN ZARIA. There is growing trade in substandard and counterfeit drugs including antibiotics around the world. The prevalence of such substandard drugs in Nigerian markets has been worrisome to both regulatory agencies and all concerned. The availability of drugs, e...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE EVALUATION OF THE ASCORBIC ACID CONTENT OF MINERAL ASCORBATE AND ASCORBIC ACID TABLETS MARKETED IN ZARIA Vitamin C otherwise known as ascorbic acid is a water soluble vitamin that is naturally present in some foods, added to others and taken as a dietary supplement. Though it is derived from glucose, humans and some other primates like guinea pigs, te...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE EVALUATION OF THE HYPOTENSIVE EFFECTS OF THE SEED AND LEAF EXTRACTS OF MORINGA OLEIFERA LAM (Moringaceae) IN LABORATORY ANIMALS Many edible plants are reliable source of medicines in many different parts of the world and are often used both as food and drug to maintain health. Moringa oleifera is one of these numerous exceptionally nutritio...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE IN VITRO BIOEQUIVALENCE EVALUATION OF SIX BRANDS OF AMOXICILLIN CAPSULE MARKETED IN DUTSE, JIGAWA STATE, NIGERIA. Bioequivalence evaluation using in vivo pharmacokinetic parameters are often assumed to be the gold standard to established product bioequivalence (BE) of immediate release solid oral dosage forms(Polli et al., 2008).However, in vitro studie...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF DIFFERENT SAMPLES OF TINIDAZOLE TABLETS Demonstration of bioequivalence using in vitro dissolution test is considered to be among the most appropriate methods of ensuring therapeutic equivalence between two or more medicinal products containing the same active pharmaceutical ingredient(s) and should be conducted for a...

PROJECT TOPIC AND MATERIAL ON COMPARATIVE PHARMACOGNOSTIC STUDIES OF THE LEAVES OF SOLANUM INCANUM LINN AND SOLANUM MELONGENA LINN (SOLANACEAE) Pharmacognosy being concerned with the description and identification of a plant including its history, commerce, collection, preparation and storage is of fundamental importance particularly for pharmacopoeial identification and quality co...

PROJECT TOPIC AND MATERIAL ON COMPARISON OF THE EFFECTS OF CIMETIDINE AND TRAMADOL ON THE DISPOSITION OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS Klaus and Jouni, (2001) stated that when two or more drugs are given together, the response may be greater or smaller than the sum of the effects of the drugs given separately. They further said that one drug may potentiate or antagonise the effects o...

PROJECT TOPIC AND MATERIAL ON CONCENTRATION OF LEAD, MANGANESE AND COPPER IN RAW WATER (FROM KUBANNI, GALMA RIVERS, AND ZARIA DAM), TREATED WATER AND SOME VEGETABLE SAMPLES IN ZARIA METROPOLIS. An essentially accurate definition of pollution is “too much of something in the wrong place”. Thus any chemical can become a “pollutant” if it is present at high concentration. Nonetheless some ...

PROJECT TOPIC AND MATERIAL ON DANIELLIA PHARMACOGNOSTIC AND BIOLOGICAL STUDIES OF THE ROOT OF OLIVERI (ROLFE) HUTCH. & DALZ. (CAESALPINIACEAE) Medicinal plants are not only important to the millions of people for whom traditional medicine is the only resource for health care and to those who use plants for various purposes in their daily lives, but also serve as a source of new structures ...

PROJECT TOPIC AND MATERIAL ON DESIGN AND DEVELOPMENT OF A STARCH-BASED MULTIFUNCTIONAL EXCIPIENT (STARGELASIL) FOR TABLET FORMULATION Tablets are intended for oral administration. Some are swallowed whole, some after being chewed, some are dissolved or dispersed in water before being administered and some are retained in the mouth where the active substance is liberated. Despite the long and c...

PROJECT TOPIC AND MATERIAL ON DETERMINATION OF CALCIUM A ND PHOSPHORUS IN STA PL E FOODS IN RICKETS P R E VA L E NT AR E A S IN KADUNA STA TE . This is a bone disease of children. It results in progressive softening and weakening of the bone structure as a result of loss of calcium and phosphate from the bone, which eventually causes destruction of the supportive gland matrix. (Blok et al., 1...

PROJECT TOPIC AND MATERIAL ON DETERMINATION OF Cd, Co, Cu, AND Fe IN WATER AND SOME VEGETABLE CROPS CULTIVATED AROUND GALMA AND KUBANNI RIVERS, ZARIA Air, soil and water possess physical and chemical properties which make them suitable for life processes. The composition of each by nature, volume and mass is constant. However, if the composition of any of these is altered by the presence of so...

PROJECT TOPIC AND MATERIAL ON DETERMINATION OF LEAD (Pb) LEVELS IN SELECTED MINING COMMUNITIES IN ZAMFARA STATE - NIGERIA Lead is a naturally occurring element that belongs to Group IVA of the periodic table and has an atomic number of 82 and atomic mass of 207.2 g/mol. It is a silver - bluish white metal that is found in small amounts in the earth‘s crust although it is rarely found natural...

PROJECT TOPIC AND MATERIAL ON DETERMINATION OF LEAD AND CADMIUM IN SOME HERBAL PREPARATIONS SOLD BY HAWKERS IN ZARIA AND ENVIRONS A metal is a substance, which conducts electricity, has a shiny luster, malleable and ductile. A non metal is a substance which doesn’t conduct electricity and is neither malleable nor ductile but brittle (Bentor,2006). Also according to Encarta Encyclopedia ...

PROJECT TOPIC AND MATERIAL ON DETERMINATION OF SOME HEAVY METALS IN FISH AND LIVESTOCK FEEDS, MANURE AND RIVERS IN SELECTED STATES IN NORTHERN NIGERIA Environmental problems are becoming global issues because of their effects on all nations of the world. These are present day major interests of political, economic, social and environmental concerns because of their potential negativ...

PROJECT TOPIC AND MATERIAL ON DEVELOPMENT AND EVALUATION OF A CO-PROCESSED EXCIPIENT FROM ACID HYDROLYZED CASSAVA STARCH, GELATIN AND LACTOSE (STARGELAC) IN TABLET FORMULATIONS. The oral route is the most common way of administering drugs and among the oral dosage forms, tablets of various kinds are the most common type of solid dosage form in contemporary use (Kaur et al., 2011)...